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Clinical Study Confirms 100% Improvement in Skin Texture with profine®

Mar.26 2026

Clinical Study Confirms 100% Improvement in Skin Texture with profine®

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MADRID, March 26, 2025 – A recent human clinical study has demonstrated that daily supplementation with profine®, a key active ingredient in select Concept 180 formulations, resulted in significant skin texture improvement in every participant. The two-month study, conducted with twelve female subjects aged 20 to 50 years, showed a 100% response rate—reinforcing the ingredient’s efficacy in supporting skin quality and texture.

Participants in the study received 250 mg of profine® daily for eight consecutive weeks. Clinical assessments conducted at the conclusion of the trial revealed that all twelve subjects experienced measurable improvement in skin texture, with no reported adverse effects. The results underscore the ingredient’s potential as a safe and effective component in targeted nutritional aesthetics protocols.

profine® is a proprietary ingredient developed through advanced extraction and purification processes, designed to support dermal matrix integrity and cellular renewal. Its inclusion in Concept 180 formulations reflects the brand’s commitment to scientifically validated ingredients that deliver observable, consistent outcomes.

“We are encouraged by these findings,” said Gema Cabañero, founder of Concept 180. “A 100% improvement rate in a clinical setting speaks to the quality and efficacy of profine®. At Concept 180, we believe in precision—every ingredient is selected not only for its individual benefits but for how it performs within a synergistic formula. Studies like this confirm that approach.”

The study adds to a growing body of clinical evidence supporting the efficacy of Concept 180’s formulations. The brand’s flagship products, including the h6 HGH Activation Capsule and rv6 Collagen Regeneration Capsule, have been developed using similar rigorous scientific principles and have been validated through both laboratory testing and real-world application across more than 50,000 users globally.

profine® is featured in select Concept 180 products available through authorized aesthetic clinics and the brand’s Tmall Global flagship store.

About profine®
profine® is a proprietary active ingredient developed for use in precision nutritional formulations. Backed by clinical research, it is designed to support skin texture, dermal health, and cellular renewal from within.

About Concept 180
Concept 180 is a Spanish professional anti-aging oral brand founded by Gema Cabañero in 1995. With a focus on precision nutrition and the proprietary Six-Dimension System, the brand offers scientifically formulated supplements that address the root causes of aging from within. Available through select aesthetic clinics and authorized partners worldwide, Concept 180 is trusted by discerning consumers, celebrities, and beauty professionals.



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